Androgenic alopecia in men usually develops in the presence of normal levels of androgens in the blood, but in the presence of so-called “peripheral androgenizm”.
This term was first proposed in 1973 by K. D. Bingham. He proved that in the balding areas of the sensitivity of hair follicles DHT receptors and activity of enzymes involved in its conversion from testosterone are much higher than in non-balding.
However, in the hair follicles was also discovered another enzyme (aromatase), which has the opposite effect, transforming testosterone into estrogens (female) hormones. In women, this enzyme is several times greater than that of men, that’s why women are not completely bald like men.
Hair follicles, depending on the sensitivity of their receptors are divided into androgenic sensitive (on top of the head) and insensitive (in the bottom-back of the head). It is believed that the sensitivity of the hair follicle to androgens lay genetically.
In susceptible hair follicles of the scalp DHT binds to androgen receptors, after which the complex of hormone – receptor activates the genes responsible for the consistent transformation of large terminal follicles in the follicles of smaller size.
Finding a cause of hair loss you should conduct appropriate treatment therapy. The most effective and safe is therapy with generic Propecia. This is a fairly new drug to treat baldness. In the European market of medicines Propecia without prescription takes the second place after sales of Viagra. This drug reduces the effects of male hormones on sebaceous glands. For this reason, Propecia is used for treatment of androgenic alopecia.
Deciding to buy Propecia, use online shops – as you will be able to get discount Propecia for sale there, this will greatly save your money.