In the course of numerous studies failed to prove that the painful muscle spasms addition to standard therapy (nonsteroidal anti-inflammatory drugs, analgesics, physical therapy, physiotherapy) leads to a more rapid regression of pain, muscle tension and improve the mobility of the spine. Muscle relaxants, in particular Soma online pills, are usually not combined with each other. In order to start treatment therapy with any muscle relaxant medication you should consult with the doctor.
For today, generic Soma is the most widely used and prescribed by doctors’ drug against back pain.
Soma has muscle relaxant action primarily at the spinal level. The drug is similar in structure to the γ-aminobutyric acid (GABA), binds to presynaptic GABA receptors, leading to a decrease in allocation of amino acids (glutamate, aspratata) and suppression of the mono-and polysynaptic activity at the spinal level, which causes decreased muscle tone; Soma also has a mild central analgesic effect.
It is well absorbed from the gastrointestinal tract and maximum concentration in the blood achieved in 2-3 hours after ingestion. The initial dose is 15mg per day, then the dose may be increased to 5mg every day until the desired effect, the drug should be taken with food. Usual doses for treatment of painful muscle spasm of 20-30mg.
Efficacy and safety of Soma pills have been proved in a double blind, placebo-controlled study. In the eight research centers, 110 patients aged 20 to 75 years received randomly Soma or placebo in combination with physical therapy and rehabilitation for 21 days.
According to research, application of Soma significantly reduced painful muscle spasm, as measured by objective instrumental method. The difference between treatment groups and placebo, which was noted already on the fourth day, gradually increased and became statistically significant at the 10th and 21th days of treatment.